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Russian scientists found in the venom of polyps-anemone’s pain killers

In the venom of marine polyps-anemone researchers, representing the Russian Academy of Sciences, found bactericidal substances that inhibit the work of the pain receptors. At the same time, according to experts, the addiction of the identified proteins do not cause, potentially making them a very promising component of painkillers.


photo: pixabay.com

Sea anemones represent one of the most primitive carnivorous creatures living on the planet today. It is assumed that the ancestors of these creatures, much like their modern followers, appeared more than half a billion years ago. With his poison of some sea anemones (in particular, the types of Metridium senile and Urticina eques), immobilize fish and other living in sea water animals. This poison with the help of special cells on the tentacles is injected into the victim when it swims past the polyp. The result is paralyzed, the animal becomes the prey of sea anemones.

Like some other poisons found in nature, substances secreted by Metridium senile and Urticina eques, were you can apply to help sentient beings and not to their detriment . Scientists came to this conclusion after studying the contained proteins Ms9a-1 and Ueq 12-1. These proteins, as it turned out, inhibits the activity of TRPA1 receptors responsible responsible for sensitivity to pain and other sensations, as well as for the development of inflammatory reactions.

Experts suggest that the identified substances will allow much closer point to the treatment of many diseases, which are based on the inflammatory process. The first experiments on laboratory mice showed that the protein Ms9a-1 and Ueq 12-1, in all likelihood, it is really possible to apply for.

Scientific works dedicated to the discovery, were published in two scientific journals — Toxins, Journal of Biological Chemistry.

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